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・ 3-fold
・ 3-fumarylpyruvate hydrolase
・ 3-Fumarylpyruvic acid
・ 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase
・ 3-Gun Nation
・ 3-Headed Shark Attack
・ 3-Heptanol
・ 3-Heptanone
・ 3-Hexanol
・ 3-Hexanone
・ 3-hexulose-6-phosphate synthase
・ 3-Hexyne
・ 3-HO-PCP
・ 3-Hydroxy-16-methoxy-2,3-dihydrotabersonine
・ 3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase
3-hydroxy-2-methylbutyryl-CoA dehydrogenase
・ 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase
・ 3-hydroxy-2-methylpyridinecarboxylate dioxygenase
・ 3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase
・ 3-hydroxy-3-isohexenylglutaryl-CoA lyase
・ 3-hydroxy-3-methylglutaryl-CoA lyase
・ 3-hydroxy-3-methylglutaryl-CoA lyase deficiency
・ 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
・ 3-Hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase
・ 3-hydroxy-D-aspartate aldolase
・ 3-Hydroxyacetophenone
・ 3-Hydroxyacyl ACP dehydrase
・ 3-hydroxyacyl-CoA dehydrogenase
・ 3-hydroxyacyl-coenzyme A dehydrogenase deficiency
・ 3-hydroxyanthranilate 3,4-dioxygenase


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3-hydroxy-2-methylbutyryl-CoA dehydrogenase : ウィキペディア英語版
3-hydroxy-2-methylbutyryl-CoA dehydrogenase

In enzymology, a 3-hydroxy-2-methylbutyryl-CoA dehydrogenase () is an enzyme that catalyzes the chemical reaction
:(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD+ \rightleftharpoons 2-methylacetoacetyl-CoA + NADH + H+
Thus, the two substrates of this enzyme are (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA and NAD+, whereas its 3 products are 2-methylacetoacetyl-CoA, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase. Other names in common use include 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase, 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase, and 2-methyl-3-hydroxy-butyryl CoA dehydrogenase. This enzyme participates in valine, leucine and isoleucine degradation.
==Structural studies==

As of 20 January 2010, 6 structure have been solved for this class of enzymes, with the PDB accession code , , , , , .

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